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Mr. Addelman sustained a brainstem stroke caused by complete occlusion of his basilar brain artery, which nourishes the part of the brain responsible for transmitting all information from the cerebral hemispheres to the rest of the body, as well as for maintaining consciousness. As the stroke progressed, (Mr. Addelman) slipped into coma, ordinarily associated with little chance for recovery. He underwent emergency revascularization surgery in an attempt to reopen the occluded blood vessel from the inside, using microcatheter technology and tPA. The microcatheter was navigated through the arterial system from an eyelash-sized incision in the leg, using digital imaging technology that allowed the identification and engagement of the obstruction with extreme precision. It was possible to eliminate the obstruction and to restore blood flow to the brainstem with sufficient speed to prevent massive infarction. He awakened from coma and, after months of intensive neurological rehabilitation therapy, has now resumed a normal life. Mr. Addelman’s rescue from certain stroke death would not have been possible without these technological innovations.

Ms. Caldwell had an abrupt blockage of a cerebral artery that caused her to fall to the ground without warning, and robbed her of movement on the right side of her body and the ability to speak. She was given intravenous medication (tPA) at a comprehensive stroke center, with an incomplete response. Perfusion CT technology was first used to determine that salvageable brain tissue was present. She then was treated by emergency endovascular surgery, entirely from within the blood vessel system, utilizing ultramodern microcatheter, hydrophilic coating and digital imaging technology to locate and eliminate the specific brain artery blockage with the highest degree of accuracy. The microcatheter was navigated the long distance from the femoral artery in her right leg to the occluded vessel in her left brain, through an incision the size of an eyelash. She was neurologically normal within 12 hours after the surgery. Ms. Caldwell’s stroke also would have resulted in permanent paralysis and loss of speech. This outcome was prevented by digital imaging, intraoperative brainwave monitoring and microcatheter and microguidewire technology.

Ms. Addington, an attorney, suffered a debilitating stroke from blockage of the middle cerebral artery that caused a loss of speech and motor power to the right side of her body. Ms. Addington’s treatment was made possible by advanced endovascular microcatheter technology and digital imaging, without which she would have been rendered permanently paralyzed and mute.

Aneurysm Embolization and Stents

Stroke Treatment Technology